Are you ready to join Connecticut Innovation’s vibrant community of innovators? Connecticut Innovations (“CI”) is Connecticut’s strategic venture capital arm, and we are passionate about serving our portfolio of 220+ companies across various industries, with strengths in life sciences, technology, and climate tech.
Come join one of our quickly growing portfolio companies, Perosphere Technologies!
About Perosphere Technologies
Perosphere Technologies is changing the way decisions are made for patients at risk for bleeding. A private medical technologies company, Perosphere is focused on development and commercialization of the novel PoC (point-of-care) Coagulometer, which informs diagnosis, treatment, and prevention through precision data, made immediately accessible to all. It is the only point-of-care (POC) diagnostic tool that effectively and swiftly tests clotting times across drug classes, including Direct Oral Anticoagulants (DOACs). The fast diagnosis and related appropriate treatment decisions the PoC Coagulometer enables will help establish a new standard of care in hospital emergency departments for patients at risk for bleeding and has the potential to improve efficiency, provide significant cost savings, and better patient outcomes.
Perosphere Technologies is funded by Advantage Capital Partners, Ambit Health Ventures, Connecticut Innovations, Ogden, and others, and has been awarded multiple federal grants from the National Institutes of Health (NIH).
Why Work at Perosphere Technologies?
• 1 out of 3 DOAC Patient Admissions are incorrectly diagnosed and treated
• Perosphere’s Coagulometer (ClotChek) is the only PoC device that can test coagulation in patients on DOACs
• ~$1 billion market opportunity across Emergency Department, DOAC Outpatient, and Heparin Inpatient segments
• $1 billion in cost reduction to hospitals and payers in the US, with improved standard of care
• Coagulometer readers and cuvettes manufactured under cGMP, ready for commercial production with launch in Europe in 2024 and U.S. to follow
• Company has doubled its employees in the last 15 months, with more planned hiring in 2024 and 2025
About the Role - Microfluidics Engineer
We are seeking a highly skilled and innovative Microfluidics Engineer with deep expertise in silicon-based MEMS (Micro-Electro-Mechanical Systems) micro processing to join our Manufacturing Operations team. In this role, you will lead the design transfer, fabrication, and characterization of our proprietary microfluidic system. Your contributions will directly impact the performance, scalability, and manufacturability of our microfluidic products.
Key Responsibilities
• Lead the design and development of our microfluidic device using silicon MEMS technology for applications in diagnostics, biosensing, or fluid control.
• Drive the microfabrication process flow, including photolithography, etching, bonding, deposition, and dicing of silicon-based components.
• Collaborate closely with cross-functional teams (mechanical, electrical, biomedical, and software engineers) to integrate microfluidic systems with electronics, sensors, and system-level platforms.
• Perform modeling, simulation, and validation of fluid dynamics in microchannels using tools such as COMSOL Multiphysics or ANSYS Fluent.
• Evaluate material compatibility, fluid handling, and performance metrics for microfluidic components and systems.
• Work with contract manufacturing partners, foundries to develop and scale microprocessing workflows.
• Document all processes, designs, and testing procedures to support IP generation, reproducibility, and regulatory filings.
• Support product development and process transfers from concept through prototyping to pilot and commercial production.
• Stay up-to-date on emerging trends, materials, and fabrication techniques in MEMS and microfluidics.
Qualifications
• Ph.D. or Master’s degree in Micro/Nano Engineering, Mechanical Engineering, Electrical Engineering, Biomedical Engineering, or a related field.
• 3–7+ years of hands-on experience in microfluidic design and silicon MEMS microfabrication.
• Strong knowledge of cleanroom processes: photolithography, DRIE, PECVD, anodic/covalent bonding, and other relevant silicon micromachining techniques.
• Experience with fluid dynamics modeling tools (e.g., COMSOL, ANSYS) and CAD tools (e.g., AutoCAD, SolidWorks).
• Familiarity with integration of microfluidics with sensors, actuators, and electronic components.
• Solid understanding of materials science related to microfluidics (e.g., silicon, glass, polymers).
• Excellent problem-solving skills, attention to detail, and the ability to work independently or in multidisciplinary teams.
• Strong written and verbal communication skills, especially around documentation, technical reporting, and presentations.
Preferred Qualifications
• Experience in diagnostics, lab-on-chip systems, or biomedical applications.
• Familiarity with wafer-level packaging, microassembly, and system integration.
• Prior experience working in a startup or fast-paced R&D environment.
• Publications or patents in relevant fields are a strong plus.
Perosphere Technologies is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.